CD244 Polyclonal Antibody, 50ul Buffer Solutions Alpha and beta families are

Alpha and beta families are further divided into acidic and basic groups

they encode different isoforms

These proteins are basic helix-loop-helix transcription factors which can act as tumor suppressors but lack DNA binding activity

The protein encoded by this gene belongs to the peptidase C12 family

The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction

CD244 Polyclonal Antibody, 50ul Buffer Solutions Alpha and beta families areCD244 encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non major histocompatibility complex (MHC) restricted killing. The interaction between NK cell and target cells via this receptor is thought to modulate NK cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.