StARD13 Polyclonal Antibody, 50ul Electronic Pipette A dominant negative mutant of

A dominant negative mutant of RNF14 has been demonstrated to inhibit the AR-mediated growth of prostate cancer

Involved in protein trafficking

Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED)

and is distributed on the surfaces of many cells and extracellular matrices

The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing

StARD13 Polyclonal Antibody, 50ul Electronic Pipette A dominant negative mutant ofSTARD13 (StAR related lipid transfer domain containing 13) encodes a protein which contains an N terminal sterile alpha motif (SAM) for protein protein interactions, followed by an ATP GTP binding motif, a GTPase activating protein (GAP) domain, and a C terminal STAR related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma