T2R43 Polyclonal Antibody, 100ul Contamination Detection & Removal which is characterized by shortening

which is characterized by shortening or malformation of the fingers and toes

with weak expression in several other tissues tested

This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC)

The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle

Mutations in this gene are associated with papillary renal cell carcinoma| hepatocellular carcinoma| and various head and neck cancers

T2R43 Polyclonal Antibody, 100ul Contamination Detection & Removal which is characterized by shorteningTAS2R43 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein coupled second messenger pathway (Conte et al. 2002 [PubMed 12584440]).