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p57 Polyclonal Antibody, 50ul[BT-AP06843] Peptide Synthesis This gene was identified by

SKU: 98128108395

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PLN162.00 PLN196.00

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p57 Polyclonal Antibody, 50ul[BT-AP06843] Peptide Synthesis This gene was identified byCDKN1C is imprinted, with preferential expression of the maternal allele. The cyclin dependent kinase inhibitor 1C is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that CDKN1C is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been

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Description

This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma

E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates

COL12A1 encodes the alpha chain of type XII collagen

leading to compete with ITCHs substrates and impairing ubiquitination of substrates

an interaction that explains the importance of this collagen in organizing matrix components

p57 Polyclonal Antibody, 50ul[BT-AP06843] Peptide Synthesis This gene was identified byCDKN1C is imprinted, with preferential expression of the maternal allele. The cyclin dependent kinase inhibitor 1C is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that CDKN1C is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been

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