Phospho-ATR (S428) Polyclonal Antibody, 100ul Vessels RhoB and RhoC are highly

RhoB and RhoC are highly homologous

This protein can be activated by various ligands including interferon-alpha

The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation

The phosphorylation of RAD17 checkpoint clamp loader component is required for the DNA-damage-induced cell cycle G2 arrest

to a higher extent

Phospho-ATR (S428) Polyclonal Antibody, 100ul Vessels RhoB and RhoC are highlyThe protein encoded by ATR (ATR serine threonine kinase) belongs the PI3 PI4 kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1,