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AR Polyclonal Antibody, 100ul[BT-AP00566] Protein Post-translational Modification The encoded protein undergoes further

SKU: 98170341505

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AR Polyclonal Antibody, 100ul[BT-AP00566] Protein Post-translational Modification The encoded protein undergoes furtherThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. AR

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Description

The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety

Moderate levels in thymus| spleen and lung

Three alternatively spliced transcripts encoding different isoforms have been described

and regulation of cell shape

and competes with E1A for binding sites in p300/CBP

AR Polyclonal Antibody, 100ul[BT-AP00566] Protein Post-translational Modification The encoded protein undergoes furtherThe androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N terminal domain, DNA binding domain, and androgen binding domain. The protein functions as a steroid hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. AR

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