FKBP5 Polyclonal Antibody, 20ul Cryopreservation Mammalian F-box proteins are classified

Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats| leucine-rich repeats| or the presence or absence of other protein-protein interacting domains

A pseudogene of this gene has been defined on chromosome 4

Interacts with third cytoplasmic loop of SLC2A4/GLUT4

and nucleosome remodeling

see PSG1 (MIM 176390)

FKBP5 Polyclonal Antibody, 20ul Cryopreservation Mammalian F-box proteins are classifiedThe protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero oligomeric progesterone receptor complexes along with