Rat Α2 Macroglobulin, ALPHA2-MG ELISA Kit, 96T Syringe Filter Contains 6 LRR (leucine-rich) repeats

Contains 6 LRR (leucine-rich) repeats

and GTP) and contain two of the three consensus motifs found in typical GTP-binding proteins

which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A

PubMed: 15456880)

Can form homomultimers and heteromultimers with GRIP1 (By similarity)

Rat Α2 Macroglobulin, ALPHA2-MG ELISA Kit, 96T Syringe Filter Contains 6 LRR (leucine-rich) repeatsIs able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a Peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight