SP-100 Polyclonal Antibody, 100ul Plasmid Preparation The cytoplasmic domain is involved
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SP-100 Polyclonal Antibody, 100ul Plasmid Preparation The cytoplasmic domain is involvedSP100 (SP100 nuclear antigen) encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia) SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO 1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for SP100; one
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