PLK2 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges Knockout studies of the mouse

Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response

Mutations in this gene have been associated with primary pulmonary hypertension

in part though interactions with the RNA polymerase II subunit RPB5

Mutations in HABP2 are associated with nonmedullary thyroid cancer and susceptibility to venous thromboembolism

alternative products:Additional isoforms seem to exist|developmental stage:Expression was detected in chondrocytes throughout the developing skeleton

PLK2 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges Knockout studies of the mouseThe protein encoded by this gene is a member of the polo family of serine threonine protein kinases that have a role in normal cell division. This gene is most abundantly expressed in testis, spleen and fetal tissues, and its expression is inducible by serum, suggesting that it may also play an important role in cells undergoing rapid cell division. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.