MKX Polyclonal Antibody, 50ul Gene Editing an autosomal dominant disorder

an autosomal dominant disorder

PPP2R1B encodes a beta isoform of the constant regulatory subunit A

protein homology

Knockout mice lacking this gene show that it is required for retinal cone bipolar cell differentiation| and that it negatively regulates potassium channel gene expression in the heart to ensure coordinated cardiac repolarization

It is thought that this family member is functional in brain due to its high expression levels there

MKX Polyclonal Antibody, 50ul Gene Editing an autosomal dominant disorderThe protein encoded by this gene is an IRX family related homeobox protein that may play a role in cell adhesion. Studies in mice suggest that this protein may be a regulator of tendon development. Two transcript variants encoding the same protein have been found for this gene.