FNBP4 Polyclonal Antibody, 100ul Cell Biology Mutations in or deletions of

Mutations in or deletions of the gene lead to growth hormone deficiency and short stature

Three transcript variants encoding two different isoforms have been described

A second copy of this gene within the centromeric copy of the duplication has been described in the literature

Two alternatively spliced transcript variants have been described

also known as suppressor of cytokine signaling (SOCS)

FNBP4 Polyclonal Antibody, 100ul Cell Biology Mutations in or deletions ofThese WW domains interact with Arg Gly rich flanked Pro rich domains found in several WW domain binding proteins (WBPs). The N terminal WW domain has the greater ligand binding ability.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,Contains 2 WW domains.,subunit: Binds FMN1. Interacts with the Arg Gly rich flanked Pro rich of KHDRBS1 SAM68. Arginine methylation in these regions has no effect on this binding.,