EGFR(Phospho Tyr1197) Polyclonal Antibody, 20ul Bottles The protein shares strong similarity

The protein shares strong similarity with a Drosophila protein which interacts with the transcription factor disco and is expressed in the nervous system

The transcript contains multiple polyadenylation and mRNA instability signals

which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM)

The specific function of this protein has not yet been determined

Alternate splicing results in multiple transcript variants of this gene

EGFR(Phospho Tyr1197) Polyclonal Antibody, 20ul Bottles The protein shares strong similarityThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.