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TERT Polyclonal Antibody, 50ul[BT-AP08144] Nucleic Acid Amplification The protein encoded by this

SKU: 99042266237

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TERT Polyclonal Antibody, 50ul[BT-AP08144] Nucleic Acid Amplification The protein encoded by thisTelomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity encoded by this gene and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres.

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Description

The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides

resulting in phosphorylation of type I receptors by type II receptors

The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family

Additional variants have been described

subunit:Interacts with the second PDZ domain of human PTP1e

TERT Polyclonal Antibody, 50ul[BT-AP08144] Nucleic Acid Amplification The protein encoded by thisTelomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity encoded by this gene and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres.

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