Raf-1(Phospho Ser301) Polyclonal Antibody, 20ul Recombinant Ab Production The carcinoembryonic antigen related cell

The carcinoembryonic antigen related cell adhesion molecule 3 directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac

Alternate splicing of this gene results in several transcript variants encoding different isoforms

MAP3K2/MEKK2

The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint

Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex

Raf-1(Phospho Ser301) Polyclonal Antibody, 20ul Recombinant Ab Production The carcinoembryonic antigen related cellThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.