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FOLR3 Polyclonal Antibody, 50ul Immune Cell Preparation Binds to pre-mRNA in spliceosome

SKU: 99158174752

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FOLR3 Polyclonal Antibody, 50ul Immune Cell Preparation Binds to pre-mRNA in spliceosomeThis gene encodes a member of the folate receptor (FOLR) family of proteins, which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5 methyltetrahydrofolate to the interior of cells. Expression of this gene may be elevated in ovarian and primary peritoneal carcinoma. This gene is present in a gene cluster on chromosome 11. Alternative splicing results in multiple transcript variants.

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Description

Binds to pre-mRNA in spliceosome C complex

Ubiquitination of type II deiodinase by the encoded protein is an important regulatory step in thyroid hormone signalling

The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A

and neutralization of pathogens

It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase

FOLR3 Polyclonal Antibody, 50ul Immune Cell Preparation Binds to pre-mRNA in spliceosomeThis gene encodes a member of the folate receptor (FOLR) family of proteins, which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5 methyltetrahydrofolate to the interior of cells. Expression of this gene may be elevated in ovarian and primary peritoneal carcinoma. This gene is present in a gene cluster on chromosome 11. Alternative splicing results in multiple transcript variants.

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