Nox3 Polyclonal Antibody, 100ul Cell Function Analysis Mutations in this gene have

Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome

This gene is unique among the cytochrome P450 genes in that it is intronless

|PTM:Subsequent to MAP3K14-dependent serine phosphorylation| p100 polyubiquitination occurs then triggering its proteasome-dependent processing

The upstream stimulatory factor 2 can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs and is involved in regulating multiple cellular processes

Contains 1 CID domain

Nox3 Polyclonal Antibody, 100ul Cell Function Analysis Mutations in this gene haveNOX3 encodes a member of the NOX family of NADPH oxidases. These enzymes have the capacity to generate superoxide and other reactive oxygen species (ROS) and transport electrons across the plasma membrane. The ROS generated by family members have been implicated in numerous biological functions including host defense, posttranlational processing of proteins, cellular signaling, regulation of gene expression, and cell differentiation. NADPH oxidase 3