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The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily

A cis-acting segment found in the 5' UTR is involved in stress-dependent induction| resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions

Mutations in this gene are associated with sensory/motor neuropathy with ataxia

It is a type I membrane protein

PSB10 Rabbit Polyclonal Antibody, 50ul DNA Fragments Take your research to theThe proteasome is a multicatalytic proteinase complex with a highly ordered ring shaped 20S core structure. The core structure is composed of 4 rings of 28 non identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP ubiquitin dependent process in a non lysosomal pathway. An essential function