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p53(Phospho-Ser366) Polyclonal Antibody, 50ul Custom RNA Oligos Inflammatory stimuli can induce IKK-mediated

SKU: 99482726547

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p53(Phospho-Ser366) Polyclonal Antibody, 50ul Custom RNA Oligos Inflammatory stimuli can induce IKK-mediatedThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

Inflammatory stimuli can induce IKK-mediated phosphorylation of PIAS1 at Ser90

Synapsin-1 encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal

Shows a preference for cleavage after small polar residues and before basic residues

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer

due to its interaction with ARL2

p53(Phospho-Ser366) Polyclonal Antibody, 50ul Custom RNA Oligos Inflammatory stimuli can induce IKK-mediatedThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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