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DARPP-32 Polyclonal Antibody, 50ul Electronic Pipette Also found in the colon

SKU: 99512164476

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DARPP-32 Polyclonal Antibody, 50ul Electronic Pipette Also found in the colonPPP1R1B encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, PPP1R1B may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for PPP1R1B.

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Description

Also found in the colon

which has a low Km for acetaldehydes

Polymorphisms in this protein appear to be tissue specific and influence protease targeting

Mutations in this gene are associated with autosomal dominant form of Charcot-Marie-Tooth disease type 1 (CMT1B) and other polyneuropathies

The AP-3 complex plays a role in protein trafficking to lysosomes and specialized organelles

DARPP-32 Polyclonal Antibody, 50ul Electronic Pipette Also found in the colonPPP1R1B encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, PPP1R1B may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for PPP1R1B.

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