IRF3 Polyclonal Antibody, 100ul DNA Libraries Synthesis dilated cardiomyopathy

dilated cardiomyopathy

and Liddle syndrome

Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy

The encoded protein binds calcium and is activated by myosin light chain kinase

The encoded protein functions as a sequence-specific transcription factor that is involved in development

IRF3 Polyclonal Antibody, 100ul DNA Libraries Synthesis dilated cardiomyopathyIRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed