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TIN2 Polyclonal Antibody, 100ul Microplate Mixer and proposed to regulate cell-cycle

SKU: 99641832367

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TIN2 Polyclonal Antibody, 100ul Microplate Mixer and proposed to regulate cell-cycleTINF2 encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The TERF1 interacting nuclear factor 2 encoded by TINF2 is a critical part of shelterin; it interacts with the three DNA binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an

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Description

and proposed to regulate cell-cycle progression during spermatogenesis

It binds the ligand sphingosine-1-phosphate with high affinity and high specificity

cts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function

this protein forms an oligomeric apoptosome

suggesting that these molecules form a complex in trophectoderm cells at the time of implantation

TIN2 Polyclonal Antibody, 100ul Microplate Mixer and proposed to regulate cell-cycleTINF2 encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The TERF1 interacting nuclear factor 2 encoded by TINF2 is a critical part of shelterin; it interacts with the three DNA binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an

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