HC-II Polyclonal Antibody, 50ul Pathway and Network Analysis This gene encodes a protein

This gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N-terminal region| and a Small MutS Related (Smr) domain near the C-terminal region

TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki| 2006)

which is characterized by lenticular myopia

and it has been determined that the diseased allele contains 40-83 CAG repeats

This protein does not contain a coiled coil region like some family members| and its exact function is unknown

HC-II Polyclonal Antibody, 50ul Pathway and Network Analysis This gene encodes a proteinSERPIND1 belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. SERPIND1 encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin,