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Phospho-Bcl-2 (T69) Polyclonal Antibody, 20ul Lysosome The protein has four IQ

SKU: 99971484967

4.3
PLN97.20 PLN130.20

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Phospho-Bcl-2 (T69) Polyclonal Antibody, 20ul Lysosome The protein has four IQBCL2 (BCL2, apoptosis regulator) encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

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Description

The protein has four IQ motifs located in the neck domain that bind calmodulin

MLCPs typically contain a catalytic protein phosphatase 1 (PP1c) subunit

thermos-stability

may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation

This protein can be secreted through non-classical pathways and functions as an extracellular mitogen

Phospho-Bcl-2 (T69) Polyclonal Antibody, 20ul Lysosome The protein has four IQBCL2 (BCL2, apoptosis regulator) encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

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