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Functional analysis classified genes that were differentially regulated by caffeine as being involved in lipid storage, chemokine activity, collagen receptor signaling, immune response, and acyl-CoA desaturase activity

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The presence of this gene translocation [t(15;17)] is used for diagnosis of APL and as a marker of response following treatment with either cytotoxic agents or tretinoin

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LPL is responsible for extracting fatty acids from the bloodstream and shuttling them into adipocytes fat cells for storage