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Christopher McGowan, a gastroenterologist who runs a weight loss clinic in North Carolina, said the side effects for both Zepbound and Wegovy are generally comparable, although his patients tend to say they fare better on Zepbound

Critical unresolved issues include identifying the molecular switches that govern the transition of autophagy from an anti- to a pro-ferroptotic state, elucidating subtype-specific differences in crosstalk mechanisms, and clarifying the molecular basis underlying proteins such as COX7A1 to exhibit opposing functions