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Savolitinib Catalog No.:M8740-10 Epub 2012 Nov 3

SKU: 10949712923

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Savolitinib Catalog No.:M8740-10 Epub 2012 Nov 3Savolitinib, also known as Volitinib, AZD6094 or HMPL 504, is an orally bioavailable inhibitor of the c Met receptor tyrosine kinase with potential antineoplastic activity. Volitinib selectively binds to and inhibits the activation of c Met in an ATP competitive manner, and disrupts c Met signal transduction pathways. This may result in cell growth inhibition in tumors that overexpress the c Met protein. Product information CAS Number: 1313725 88 0

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Description

Epub 2012 Nov 3

29-triazaspiro[pentacyclo[23

5H-thieno[3

PC-9VanR (EGFRExon 19 deletion/T790M)

significantly enhanced cell growth inhibition

Savolitinib Catalog No.:M8740-10 Epub 2012 Nov 3Savolitinib, also known as Volitinib, AZD6094 or HMPL 504, is an orally bioavailable inhibitor of the c Met receptor tyrosine kinase with potential antineoplastic activity. Volitinib selectively binds to and inhibits the activation of c Met in an ATP competitive manner, and disrupts c Met signal transduction pathways. This may result in cell growth inhibition in tumors that overexpress the c Met protein. Product information CAS Number: 1313725 88 0

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