Losartan D4 3835 Eur J Clin Pharmacol

Eur J Clin Pharmacol

8-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3H-pyrrolo(4

GSK429286A slightly inhibits RSK and p70S6K with IC50 of 0

PubMed Central PMCID: PMC4866744

000-fold greater potency than that of SU 5402

Losartan D4 3835 Eur J Clin PharmacolLosartan D4 (DuP 753 D4) is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM. Product information CAS Number: 1030937 27 9 Molecular Weight: 426. 94 Formula: C22H23ClN6O Synonym: DuP 753 D4 Cozaar D4 Chemical Name: (2 butyl 4 chloro 1 {[2' (2H 1,2,3,4 tetrazol 5 yl)(2,3,5,6 H) [1,1' biphenyl] 4 yl]methyl} 1H imidazol 5 yl)methanol Smiles: