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Y-27632 - Rock Inhibitor. CAS# 146986-50-7 60174 Smiles: OC(=O)C1=CC2=NC(NC3=CC(Cl)=CC=C3)=C3C=CN=CC3=C2C=C1

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Y-27632 - Rock Inhibitor. CAS# 146986-50-7 60174 Smiles: OC(=O)C1=CC2=NC(NC3=CC(Cl)=CC=C3)=C3C=CN=CC3=C2C=C1Y 27632, CAS No. 146986 50 7, is a widely used, selective inhibitor of the Rho associated protein kinase p160ROCK with a Ki value at ~ 0. 14 M. In many studies, it was shown and used to enhance the survival and cloning efficiency of many primary cell types after single cell dissociation without affecting their self renewal properties, including hESC iPSCs, neural stem cells, intestinal stem cells, and mammary epithelial cells. Product information CAS

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Smiles: OC(=O)C1=CC2=NC(NC3=CC(Cl)=CC=C3)=C3C=CN=CC3=C2C=C1

Rajeshkumar NV

283 and >400 μM respectively)

Y-27632 was orally dosed at 30 mg/kg to significantly decrease blood pressure

as well as decreased hyperplasia

Y-27632 - Rock Inhibitor. CAS# 146986-50-7 60174 Smiles: OC(=O)C1=CC2=NC(NC3=CC(Cl)=CC=C3)=C3C=CN=CC3=C2C=C1Y 27632, CAS No. 146986 50 7, is a widely used, selective inhibitor of the Rho associated protein kinase p160ROCK with a Ki value at ~ 0. 14 M. In many studies, it was shown and used to enhance the survival and cloning efficiency of many primary cell types after single cell dissociation without affecting their self renewal properties, including hESC iPSCs, neural stem cells, intestinal stem cells, and mammary epithelial cells. Product information CAS

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