Volasertib Catalog No.:M10873-2 2013 Oct 24

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Volasertib Catalog No.:M10873-2 2013 Oct 24Volasertib, also known as BI 6727, is a dihydropteridinone Polo like kinase 1 (Plk1) inhibitor with potential antineoplastic activity. BI 6727 selectively inhibits Plk1, inducing selective G2 M arrest followed by apoptosis in a variety of tumor cells while causing reversible cell arrest at the G1 and G2 stage without apoptosis in normal cells. BI 6727 is highly potent (enzyme IC(50) = 0. 87 nmol L, EC(50) = 11 37 nmol L on a panel of cancer cell

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