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Olcegepant - CAS# 204697-65-4 Catalog No.:M10814-10 Eur J Clin Pharmacol

Olcegepant - CAS# 204697-65-4 Catalog No.:M10814-10 Eur J Clin Pharmacol

Name: Olcegepant - CAS# 204697-65-4 Catalog No.:M10814-10 Eur J Clin Pharmacol
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Olcegepant - CAS# 204697-65-4 Catalog No.:M10814-10 Eur J Clin PharmacolOlcegepant, also known as BIBN 4096 or BIBN 4096BS is is the first potent and selective non peptide antagonist of the calcitonin gene related peptide 1 (CGRP1) receptor, a key modulator in neurogenic inflammatory pain. In preclinical studies, olcegepant attenuated arterial dilation induced by CGRP or electrical stimulation. In a phase II clinical trial, olcegepant reduced the severity of headache in 60% of migraine sufferers and met secondary

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Eur J Clin Pharmacol

Smiles: O=C(NC1C=CC(=CC=1)C1=CC=NC(NC2C=CC(=CC=2)N2CCOCC2)=N1)[C@@H]1CCCN1

Formula: C20H24O4

which may have potential application in treating anemia of chronic disease

CAS Number: 480449-71-6

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