Tenovin 6 Hydrochloride iclesonide 182004-65-5

182004-65-5

Cleton-Jansen AM

also known as KDR/FLK-1) tyrosine kinase with potential antineoplastic activity

thereby inducing apoptosis of HER2-amplified breast cancer cells

It is also used to prevent further heart problems after myocardial infarction and to prevent headaches in those with migraines

Tenovin 6 Hydrochloride iclesonide 182004-65-5Tenovin 6, also known as Tnv 6, is a bioactive small molecule SIRT2 inhibitor with anti neoplastic activity. Inhibition of the Sirtuin class of protein deacetylases with activation of p53 function is associated with the pro apoptotic effects of Tnv 6 in many tumors. Tnv 6 causes non genotoxic cytotoxicity, without adversely affecting human clonogenic hematopoietic progenitors in vitro, or murine hematopoiesis. Mechanistically, exposure of CLL cells to