PROTAC BET degrader-2 Catalog No.:M7998-2 CC1=CC(=NC2=CC=CC=C21)N1CCCCC1

CC1=CC(=NC2=CC=CC=C21)N1CCCCC1

30-dimethoxy-15

Addition of 2 μM Ionomycin to LCLC 103H cells causes an instantaneous increase in intracellular Ca2+ concentration from 50 to 180 nM

2019 May 6

Smiles: CCOC1=CC=CC2[C@@H]3C=CC[C@@H]3[C@@H](NC=21)C1C=CC(=CC=1)C(O)=O

PROTAC BET degrader-2 Catalog No.:M7998-2 CC1=CC(=NC2=CC=CC=C21)N1CCCCC1PROTAC BET degrader 2 is a highly potent degrader of Bromodomain and Extra Terminal (BET) proteins with an IC50 value of 9. 6 nM in cell growth inhibition in the RS4; 11 cells and capable of achieving tumor regression. Product information CAS Number: 2093388 33 9 Molecular Weight: 770. 84 Formula: C41H42N10O6 Chemical Name: 4 [(3 cyclopropyl 1 ethyl 1H pyrazol 5 yl)amino] 7 (3, 5 dimethyl 1, 2 oxazol 4 yl) N {3 [2 (2, 6 dioxopiperidin 3 yl) 1 oxo 2, 3