kobe2602 astin InChi: InChI=1S/C21H27N3O2/c1-16-3-4-17(2)20(15-16)26-14-11-23-19-7-12-24(13-8-19)21(25)18-5-9-22-10-6-18/h3-6

InChi: InChI=1S/C21H27N3O2/c1-16-3-4-17(2)20(15-16)26-14-11-23-19-7-12-24(13-8-19)21(25)18-5-9-22-10-6-18/h3-6

Gemfibrozil is a peroxisome proliferator receptor alpha agonist

Marbofloxacin is a fluoroquinolone antimicrobial agent developed exclusively for veterinary use

Formula: C8H18N3O8P

Chemical Name: 5-[(4-ethylphenyl)methylidene]-2-sulfanylidene-1

kobe2602 astin InChi: InChI=1S/C21H27N3O2/c1-16-3-4-17(2)20(15-16)26-14-11-23-19-7-12-24(13-8-19)21(25)18-5-9-22-10-6-18/h3-6Kobe2602, is analog of Kobe0065 , is is a potent and selective RAS inhibitor, which exhibit inhibitory activity toward H Ras GTP c Raf 1 binding both in vivo and in vitro. Kobe2602 effectively inhibits both anchorage dependent and independent growth and induce apoptosis of H ras(G12V) transformed NIH 3T3 cells, which is accompanied by down regulation of downstream molecules such as MEK ERK, Akt, and RalA as well as an upstream molecule, Son of