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WS6 - β Cell Proliferation Inducer. CAS# 1421227-53-3 201 Smiles: OC(=O)C(S)=CC1=CNC2=CC=C(F)C=C12

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WS6 - β Cell Proliferation Inducer. CAS# 1421227-53-3 201 Smiles: OC(=O)C(S)=CC1=CNC2=CC=C(F)C=C12WS6, CAS No. 1421227 53 3, is a highly potent and selective small molecule that promotes pancreatic cell proliferation in rodent and human primary islets, identified by a high throughput, cell based screening using rodent pancreatic cells. It can induce proliferation of mouse R7T1 cells with an EC50 ~0. 28 M, and induce up to 4% of rat cells and 3% of human cells to proliferate, with a similar EC50 of 0. 4 M. WS6 induces proliferation of primary rat

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Description

Smiles: OC(=O)C(S)=CC1=CNC2=CC=C(F)C=C12

J Transl Med

Formula: C20H20N4O3

InChiKey: LLJJDLHGZUOMQP-UHFFFAOYSA-N

RG108 was used at 10-100 µM final concentration in various in vitro assays

WS6 - β Cell Proliferation Inducer. CAS# 1421227-53-3 201 Smiles: OC(=O)C(S)=CC1=CNC2=CC=C(F)C=C12WS6, CAS No. 1421227 53 3, is a highly potent and selective small molecule that promotes pancreatic cell proliferation in rodent and human primary islets, identified by a high throughput, cell based screening using rodent pancreatic cells. It can induce proliferation of mouse R7T1 cells with an EC50 ~0. 28 M, and induce up to 4% of rat cells and 3% of human cells to proliferate, with a similar EC50 of 0. 4 M. WS6 induces proliferation of primary rat

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