WS 3 TRPM8 antagonist 314 Preclinical modeling of combined phosphatidylinositol-3-kinase

Preclinical modeling of combined phosphatidylinositol-3-kinase inhibition with endocrine therapy for estrogen receptor-positive breast cancer

InChiKey: OXQNLLVUVDAEHC-OAQYLSRUSA-N

is a potent small-molecule inhibitor of WNT signaling with good oral pharmacokinetics

It inhibited the binding of Ral to its effector RALBP1

100 μM has significant cellular toxicity on C2C12 cells

WS 3 TRPM8 antagonist 314 Preclinical modeling of combined phosphatidylinositol-3-kinaseWS 3 is an agonist of TRPM8 with an EC50 of 3. 7 M. Product information CAS Number: 39711 79 0 Molecular Weight: 211. 34 Formula: C13H25NO Chemical Name: N ethyl 5 methyl 2 (propan 2 yl)cyclohexane 1 carboxamide Smiles: CC(C)C1CCC(C)CC1C(=O)NCC InChiKey: VUNOFAIHSALQQH UHFFFAOYSA N InChi: InChI=1S C13H25NO c1 5 14 13(15)12 8 10(4)6 7 11(12)9(2)3 h9 12H,5 8H2,1 4H3,(H,14,15) Technical Data Appearance: Solid Power Purity: 98% (or refer to the