Santacruzamate A - CAS# 1477949-42-0 0022 Matsumoto S

Matsumoto S

Weinstein SF

Molecular Weight: 346

Absorption is relatively rapid in dogs but slower in mice (10 mg/kg)

A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models

Santacruzamate A - CAS# 1477949-42-0 0022 Matsumoto SSantacruzamate A, CAS No. 1477949 42 0, is a potent and selective histone deacetylase inhibitor from the Panamanian marine cyanobacterium cf. Symploca sp. CAY10683 inhibits HDAC2 and HDAC6 with IC50 values of 0. 119 and 434 nM, respectively. Product information CAS Number: 1477949 42 0 Molecular Weight: 278. 35 Formula: C15H22N2O3 Synonym: CAY10683 CAY 10683 Santacruzamate A CAY 10683 Chemical Name: ethyl (4 oxo 4 (phenethylamino)butyl)carbamate