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LCH 7749944 60308 1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoyl)sulfamoyl)-2-((trifluoromethyl)sulfonyl)phenyl)amino)-4-(phenylthio)butyl)piperazin-1-yl)-7-oxoheptanamido)-3
LCH 7749944 60308 1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoyl)sulfamoyl)-2-((trifluoromethyl)sulfonyl)phenyl)amino)-4-(phenylthio)butyl)piperazin-1-yl)-7-oxoheptanamido)-3
LCH 7749944 60308 1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoyl)sulfamoyl)-2-((trifluoromethyl)sulfonyl)phenyl)amino)-4-(phenylthio)butyl)piperazin-1-yl)-7-oxoheptanamido)-3
LCH 7749944 60308 1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoyl)sulfamoyl)-2-((trifluoromethyl)sulfonyl)phenyl)amino)-4-(phenylthio)butyl)piperazin-1-yl)-7-oxoheptanamido)-3

LCH 7749944 60308 1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoyl)sulfamoyl)-2-((trifluoromethyl)sulfonyl)phenyl)amino)-4-(phenylthio)butyl)piperazin-1-yl)-7-oxoheptanamido)-3

SKU: 20940419120

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LCH 7749944 60308 1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoyl)sulfamoyl)-2-((trifluoromethyl)sulfonyl)phenyl)amino)-4-(phenylthio)butyl)piperazin-1-yl)-7-oxoheptanamido)-3LCH 7749944 is a novel and potent p21 activated kinase 4 (PAK4) inhibitor that suppresses proliferation and invasion in human gastric cancer cells through downregulation of PAK4 c Src EGFR cyclin D1 pathway and causes successful inhibition of EGFR activity. Product information CAS Number: 796888 12 5 Molecular Weight: 350. 41 Formula: C20H22N4O2 Chemical Name: N2 (3 methoxyphenyl) N4 ((tetrahydrofuran 2 yl)methyl)quinazoline 2,4 diamine Smiles:

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Description

1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoyl)sulfamoyl)-2-((trifluoromethyl)sulfonyl)phenyl)amino)-4-(phenylthio)butyl)piperazin-1-yl)-7-oxoheptanamido)-3

GSK-J4 was used at 30 µM final concentration in cellular assays

to a lesser extent

is a cell-permeable

PubMed PMID: 24458356

LCH 7749944 60308 1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoyl)sulfamoyl)-2-((trifluoromethyl)sulfonyl)phenyl)amino)-4-(phenylthio)butyl)piperazin-1-yl)-7-oxoheptanamido)-3LCH 7749944 is a novel and potent p21 activated kinase 4 (PAK4) inhibitor that suppresses proliferation and invasion in human gastric cancer cells through downregulation of PAK4 c Src EGFR cyclin D1 pathway and causes successful inhibition of EGFR activity. Product information CAS Number: 796888 12 5 Molecular Weight: 350. 41 Formula: C20H22N4O2 Chemical Name: N2 (3 methoxyphenyl) N4 ((tetrahydrofuran 2 yl)methyl)quinazoline 2,4 diamine Smiles:

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