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[1] While the risk of contamination in an unopened, sealed pen is low even after expiration, the sterility and integrity of the delivery system cannot be guaranteed beyond the expiration date

In a key secondary endpoint, from a baseline weight of 189 lb., Mounjaro reduced participants' weight by a mean of 14 lb.* (5 mg), 15 lb.* (10 mg) and 17 lb.* (15 mg) compared to 2 lb

A patient with BMI 25.5 who has tried multiple diets, has prediabetes, and wants to prevent progression to diabetes is a reasonable candidate for compounded tirzepatide even though they fall slightly below FDA approval criteria

While it does activate GLP-1 receptors like semaglutide, it has five times stronger affinity for GIP receptors, creating a metabolic signal your body doesn't get from GLP-1 medications alone

Appetite suppression has noticeably weakened, and old eating patterns are starting to return