FR 180204 Size:Solid 2 mg Solubility: DMSO up to 100

Solubility: DMSO up to 100 mM

Please note: exact ratio for use and transfection efficiency is dependent on cell line used

InChi: InChI=1S/C5H10N2O7P2

Smiles: CNC(=O)C1=CC(=CC=C1)C1=CC=C2C(=N1)N=C(N=C2N1CCOC[C@@H]1C)N1CCOC[C@@H]1C

It has very weak or no activity targeting the other HDACs (2-40 µM)

FR 180204 Size:Solid 2 mg Solubility: DMSO up to 100FR180204 is a novel and selective inhibitor of extracellular signal regulated kinase (ERK), which may be a potential new therapy for rheumatoid arthritis. FR180204 showed activity to inhibit ERKs (IC50 values are 0. 14 and 0. 31 M for ERK2 and ERK1 respectively). Product information CAS Number: 865362 74 9 Molecular Weight: 327. 34 Formula: C18H13N7 Synonym: FR180204 FR 180204 Chemical Name: 5 {2 phenylpyrazolo[1,5 a]pyridin 3 yl} 2H pyrazolo[3,4