Co-1686 - CAS# 1374640-70-6 Catalog No.:M111-2S CAS Number: 1154097-71-8

CAS Number: 1154097-71-8

InChi: InChI=1S/C55H83N17O21S3/c1-20-33(69-46(72-44(20)58)25(12-31(57)76)64-13-24(56)45(59)82)50(86)71-35(41(26-14-61-19-65-26)91-54-43(39(80)37(78)29(15-73)90-54)92-53-40(81)42(93-55(60)88)38(79)30(16-74)89-53)51(87)66-22(3)36(77)21(2)47(83)70-34(23(4)75)49(85)63-10-8-32-67-28(18-94-32)52-68-27(17-95-52)48(84)62-9-7-11-96(5)6/h14

and delay in tumor recurrence

prevents Stat3 phosphorylation/activation

Brain Penetrant LRRK2 Inhibitorn (2012) ACS Med

Co-1686 - CAS# 1374640-70-6 Catalog No.:M111-2S CAS Number: 1154097-71-8CO 1686, CAS No. 1374640 70 6, is an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M, and the Ki values for EGFRL858R T790M and EGFRWT are 21. 5 nM and 303. 3 nM, respectively. Product information CAS Number: 1374640 70 6 Molecular Weight: 555. 55 Formula: C27H28F3N7O3 Synonym: Rociletinib AVL 301 Chemical Name: N (3 ((2 ((4 (4 acetylpiperazin 1 yl) 2 methoxyphenyl)amino) 5