GNE-493 Size:100 mg solid Formula: C16H15FN2O4

Formula: C16H15FN2O4

Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs

Molecular Weight: 287

2003 Oct 17

InChi: InChI=1S/C20H11N5OS/c21-11-13-16-10-12(22-20(26)17-6-3-9-27-17)7-8-25(16)19-18(13)23-14-4-1-2-5-15(14)24-19/h1-10H

GNE-493 Size:100 mg solid Formula: C16H15FN2O4GNE 493 (compound 5) is a potent, selective and orally available dual inhibitor of pan PI3 kinase and mTOR with IC50 of 3. 4 nM, 12 nM, 16 nM, 16 nM and 32 nM for PI3K, PI3K, PI3K, PI3K and mTOR, respectively. Product information CAS Number: 1033735 94 2 Molecular Weight: 372. 44 Formula: C17H20N6O2S Chemical Name: 2 (2 (2 aminopyrimidin 5 yl) 4 morpholinothieno[3,2 d]pyrimidin 6 yl)propan 2 ol Smiles: