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PFI-4 - BRPF1 Bromodomain Inhibitor. CAS# 900305-37-5 0020 Solubility: DMSO: 77 mg/mL (185

PFI-4 - BRPF1 Bromodomain Inhibitor. CAS# 900305-37-5 0020 Solubility: DMSO: 77 mg/mL (185

Name: PFI-4 - BRPF1 Bromodomain Inhibitor. CAS# 900305-37-5 0020 Solubility: DMSO: 77 mg/mL (185
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PFI-4 - BRPF1 Bromodomain Inhibitor. CAS# 900305-37-5 0020 Solubility: DMSO: 77 mg/mL (185PFI 4, CAS No. 900305 37 5, is a potent, selective and cell permeable BRPF1 bromodomain inhibitor. It binds to BRPF1B with a Kd of 13 nM (ITC). It has general >100 fold selectivity against other bromodomains including BRPF2, BRPF3 and BRD4. It reduces recovery time in triple BRD cell construct in FRAP and is potent in cells with IC50 250 nM, while showing no effect on BRPF1A. Product information CAS Number: 900305 37 5 Molecular Weight: 380. 44

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Description

Solubility: DMSO: 77 mg/mL (185

1 μM) inhibits EGFR potently and irreversibly

Molecular Weight: 381

but not to the extent of glucocorticoid inhibition

Chemical Name: 3-((3R

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