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RG3039 0081 Acute and Chronic Hyperglycemia Elicit

SKU: 24248795499

4.1
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RG3039 0081 Acute and Chronic Hyperglycemia ElicitRG3039 (PF 06687859, PF 6687859, Quinazoline 495) is an orally bioavailable and brain penetrant inhibitor of the mRNA decapping enzyme DcpS with IC50 of 4. 2 nM and IC90 of 40 nM, respectively. Product information CAS Number: 1005504 62 0 Molecular Weight: 432. 35 Formula: C21H23Cl2N5O Synonym: PF 06687859 Chemical Name: 5 ((1 (2,6 dichlorobenzyl)piperidin 4 yl)methoxy)quinazoline 2,4 diamine Smiles:

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Description

Acute and Chronic Hyperglycemia Elicit JIP1/JNK-Mediated Endothelial Vasodilator Dysfunction of Retinal Arterioles

DMH-1 effectively inhibits the bone morphogenic protein (BMP) ALK2 receptor (IC50 = 108 nM)

Formula: C27H26ClN3O7S2

and proteasome-dependent manner in HCT116 cells and Mino cells

Solubility: DMSO : 41

RG3039 0081 Acute and Chronic Hyperglycemia ElicitRG3039 (PF 06687859, PF 6687859, Quinazoline 495) is an orally bioavailable and brain penetrant inhibitor of the mRNA decapping enzyme DcpS with IC50 of 4. 2 nM and IC90 of 40 nM, respectively. Product information CAS Number: 1005504 62 0 Molecular Weight: 432. 35 Formula: C21H23Cl2N5O Synonym: PF 06687859 Chemical Name: 5 ((1 (2,6 dichlorobenzyl)piperidin 4 yl)methoxy)quinazoline 2,4 diamine Smiles:

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