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ANA-12 Catalog No.:M8450-10 IL-1β and IL-6 in the

SKU: 25339122561

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SEK85.00 SEK133.00

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ANA-12 Catalog No.:M8450-10 IL-1β and IL-6 in theANA 12 is aTrkB receptor antagonist. ANA 12 showed direct and selective binding to TrkB and inhibited processes downstream of TrkB without altering TrkA and TrkC functions. Systemic administration of ANA 12 to adult mice decreased TrkB activity in the brain without affecting neuronal survival. Mice administered ANA 12 demonstrated reduced anxiety and depression related behaviors on a variety of tests predictive of anxiolytic and antidepressant

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Description

IL-1β and IL-6 in the blood serum

947669-86-5

11bR)-3-hydroxy-10

Purvalanol A does not inhibit transcription under cell-free conditions

15 μM for SNU-475 cells and 200 μM for SNU-182 cells

ANA-12 Catalog No.:M8450-10 IL-1β and IL-6 in theANA 12 is aTrkB receptor antagonist. ANA 12 showed direct and selective binding to TrkB and inhibited processes downstream of TrkB without altering TrkA and TrkC functions. Systemic administration of ANA 12 to adult mice decreased TrkB activity in the brain without affecting neuronal survival. Mice administered ANA 12 demonstrated reduced anxiety and depression related behaviors on a variety of tests predictive of anxiolytic and antidepressant

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