CERC-501 - CAS# 1174130-61-0 size:10mg solid InChiKey: MVOZLTFXYGHZPM-UHFFFAOYSA-N

InChiKey: MVOZLTFXYGHZPM-UHFFFAOYSA-N

AZD-2281 (Olaparib) is a single digit nanomolar inhibitor of both PARP-1 and PARP-2 that shows standalone activity against BRCA1-deficient breast cancer cell lines

5-c]quinolin-2(3H)-one

Tyrosine kinase inhibitor SU11274 increased tumorigenicity and enriched for melanoma-initiating cells by bioenergetic modulation

PubMed PMID: 19122279

CERC-501 - CAS# 1174130-61-0 size:10mg solid InChiKey: MVOZLTFXYGHZPM-UHFFFAOYSA-NCERC 501, also known as JNJ 67953964, LY 2456302 and Aticaprant, CAS No. 1174130 61 0, is a potent, selective, short acting antagonist of the opioid receptor (KOR) (Ki = 0. 81 nM vs. 24. 0 nM and 155 nM for the opioid receptor (MOR) and opioid receptor (DOR). Aticaprant is under development for the treatment of major depressive disorder and substance use disorders including alcoholism, nicotine addiction, and illicit drug dependence. Aticaprant has