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Azeliragon HCl - CAS# 1284150-65-7 66049 8°C at 130 min post

Azeliragon HCl - CAS# 1284150-65-7 66049 8°C at 130 min post

Name: Azeliragon HCl - CAS# 1284150-65-7 66049 8°C at 130 min post
Brand: avramcheva.com
SKU: 26561094941
Price: 65.00 USD
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SKU: 26561094941

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Azeliragon HCl - CAS# 1284150-65-7 66049 8°C at 130 min postAzeliragon HCl, CAS No. 1284150 65 7, also known as TTP488 and PF 04494700, is a potent and orally active RAGE inhibitor. RAGE (receptor for advanced glycation endproducts) is a pattern recognition receptor, which affects the movement of amyloid, an Alzheimer's associated protein, into the brain. In preclinical studies, azeliragon decreased brain amyloid in mice and improved their performance on behavior tests. Azeliragon is a promising agent for for

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Description

8°C at 130 min post injection

PubMed PMID: 23244871

2019 Mar 7

InChi: InChI=1S/C19H21NO2/c1-13(15-7-8-18-19(11-15)22-10-9-21-18)20-17-12-16(17)14-5-3-2-4-6-14/h2-8

5 μM after 24 and 48 h of treatment

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