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Lonafarnib - CAS# 193275-84-2 702 34)/b18-16+/t20-

SKU: 28633038125

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Lonafarnib - CAS# 193275-84-2 702 34)/b18-16+/t20-Lonafarnib is a farnesyl transferase inhibitor. Structurely, it is also a synthetic tricyclic derivative of carboxamide with antineoplastic properties. Lonarfanib binds to and inhibits farnesyl transferase, an enzyme involved in the post translational modification and activation of Ras proteins. Ras proteins participate in numerous signalling pathways (proliferation, cytoskeletal organization), and play an important role in oncogenesis. Mutated ras

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Description

34)/b18-16+/t20-

H2O/c12-10(14)16-6-9(7-17-11(13)15)8-4-2-1-3-5-8

2014 May-Jun

is potentially for the treatment of malaria

Smiles: COC1C2C=COC=2C(OC[C@@H](O)C(C)(C)O)=C2OC(=O)C=CC2=1

Lonafarnib - CAS# 193275-84-2 702 34)/b18-16+/t20-Lonafarnib is a farnesyl transferase inhibitor. Structurely, it is also a synthetic tricyclic derivative of carboxamide with antineoplastic properties. Lonarfanib binds to and inhibits farnesyl transferase, an enzyme involved in the post translational modification and activation of Ras proteins. Ras proteins participate in numerous signalling pathways (proliferation, cytoskeletal organization), and play an important role in oncogenesis. Mutated ras

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