Epirubicin Hydrochloride alexin 5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide hydrochloride

5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide hydrochloride

Molecular Weight: 500

CAS Number: 1257044-40-8

Hesperadin (IC50 = 40 nM) blocked recombinant trypton histone H3 phosphorylation by T

which is a nerve that activates the vomiting center in the medulla oblongata

Epirubicin Hydrochloride alexin 5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide hydrochlorideEpirubicin is an anthracycline drug used for chemotherapy. It can be used in combination with other medications to treat breast cancer in patients who have had surgery to remove the tumor. Similarly to other anthracyclines, epirubicin acts by intercalating DNA strands. Intercalation results in complex formation which inhibits DNA and RNA synthesis. It also triggers DNA cleavage by topoisomerase II, resulting in mechanisms that lead to cell death.