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Netupitant - CAS# 290297-26-6 450 Formula: C16H25ClN2O4

SKU: 31356949543

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Netupitant - CAS# 290297-26-6 450 Formula: C16H25ClN2O4Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity. Netupitant competitively binds to and blocks the activity of the human substance P NK1 receptors in the central nervous system (CNS), thereby inhibiting NK1 receptor binding of the endogenous tachykinin neuropeptide substance P (SP), which may result in the prevention of chemotherapy induced nausea and vomiting (CINV). Product information CAS Number:

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Description

Formula: C16H25ClN2O4

3(34Dihydroxycinnamoyl)quinate

Smiles: CO[C@]1(C)C[C@@H](O[C@@H](C)[C@@]1(O)CNCCC)O[C@H]1[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)CN[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC(=O)[C@@H]1C

Formula: C24H26N2O3

Pirfenidone significantly attenuates the score when administered in Bleomycin (BLM)-treated mice (P<0

Netupitant - CAS# 290297-26-6 450 Formula: C16H25ClN2O4Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity. Netupitant competitively binds to and blocks the activity of the human substance P NK1 receptors in the central nervous system (CNS), thereby inhibiting NK1 receptor binding of the endogenous tachykinin neuropeptide substance P (SP), which may result in the prevention of chemotherapy induced nausea and vomiting (CINV). Product information CAS Number:

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